As is typical of your past questions, you are being hyperbolic and absurd.

ASRHE [suggests a ventilation rate of 40 to 70 CFM][1] - if we took 70 CFM and 4 air changes per hour, your house would be a 10 foot cube, roughly. As far as I recall past mention of your purported house, it will be much, much, much larger than that. 

As such, the ACH (which would still be at most 70 per that standard) will be far below 4. And the surface area of poorly insulated or uninsulated building
to enclose that area will be large, and losing a metric-butt-ton® of heat as a result.

I've run the numbers in past answers.
https://diy.stackexchange.com/questions/94968/are-btus-only-calculated-using-square-feet/94978#94978

  [1]: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=13&ved=0ahUKEwi09ff0s_3WAhWCx4MKHceEDHsQFghdMAw&url=https%3A%2F%2Fwww.ashrae.org%2FFile%2520Library%2FdocLib%2FPublic%2F20031231103644_266.pdf&usg=AOvVaw0sVqNTil5I8Hn1KDvlad8H