This question already has an answer here:
I've read to not drill a hole greater than 1/3 the depth of the board (I want to drill a 3/4" hole in a 12" board for wiring, so that won't be an issue) as well as not to do it within two inches of the edges. Mine will be approximately 6" from one end.
Are there any restrictions as to how close to the ends of the board I can go with the hole?
Is the "end" of a joist, one of its "edges" (and therefore any holes must be 2" from the end)?