The way to handle a long extension ladder safely is to learn how. That sounds tautological, but the point is that you shouldn't mess with it until you've had training and practice , in a safe, open area. If a ladder that long is too much for you to handle, then leave it to the experts.
If you want to learn, here are a few pointers.
1) Make sure the rope is clear of obstructions and that the pulley runs smoothly.
2) Keep the ladder close to the house when raising it, and keep it dead vertical while raising it (not easy). Once it's long enough -- which is to say well above roof level, rest it against the roof and slowly pull the base away until it's at the recommended angle.
3) Before stepping onto the ladder make sure that (a) the rope is tied to a rung as a safety factor to avoid accidental telescoping, (b) the ladder is not tilted to either side, and (c) the ladder's feet are solidly seated on the ground. I recommend a base stabilizer, which is a roughly U-shaped bar that bolts to the ladder and provides outrigger feet to stop the ladder from falling sideways.
To lower the ladder, reverse these steps.