Home made mesquite flooring. What is the best floor finish? Low traffic but subject to spills...this is for the man cave. Installing diy mesquite floor tiles, 4 - 6" width, random lengths. Aprox 1/4 inch mesquite glued to 3/4 inch construction grade plywood....avoiding voids.
It's hard to beat Polyurethane for durability. I have had good success with both water based and solvent based versions. Get the stuff made for floors, probably two coats would do you. You don't want it too smooth or you'll die when it's wet.
That is, unless you have small children, then I would suggest poured concrete ;)