Technically there should be no difference to the load if the Hot and Neutral are reversed. AC voltage and current switch 60 times per second which means they automatically reverse voltage.
What can happen is if the Appliance manufacturer does a bad job and connects the neutral side to the chassis which should never be done you might notice. The neutral side of the AC circuit is ultimately connected to the Earth Ground at the main service panel with forces it be close to zero volts compared to GND. The neutral wire will not be at zero volts because it carries current and with the voltage drop (IR) across the wiring infrastructure will move around because other loads throughout the house share the neutral bus within the wiring infrastructure. Without the Ground bus connection at the service panel the hot would be 60+ and 60- and the neutral would be 60- and 60+.
The electrons flowing in the wire have no idea which is hot or neutral. Hot and Neutral is a cookbook solution for Electricians. If you run 240 Volts there is no need for a neutral wire. A 240-volt load won't even use it. Other parts of the world with 220 or 240 volts don't even have the concept of a neutral wire. The neutral wire concept originated with Thomas Edison DC electric homes where you could provide a +120 to GND and GND to -120 volts DC.
Eventually, AC replaced DC and the AC voltage was given 120V RMS to be equivalent to a DC circuit. 120 Volts AC has a peak voltage of 169.7 Volts. With a 60 Hz AC circuit there is time at 120 times per second that there is zero voltage applied to the AC line. Every 8.33 ms the entire electrical grid is a zero voltage.