I'm making a small 12x16ft workshed. I want to go 24" o.c. on the walls and rafters (rafters may be 2x6, or 2x4 with supporting members), both for cost saving, and because it will create less thermal bridges in the wall. Due to what's available here, I will be using 7/16 OSB sheathing for the walls and roof, which should work with the longer spacing. I can also go 5/8 drywall on the ceiling to prevent sagging.
However, I can't seem to find much information on 2x4 24 o.c. load bearing walls. Not sure how common they are. Is there any issues with these types of walls?