You only need the two line wires and at least a 610 gauge ground wire. Neutral is just a waste of copper and money unless you're going to use a 14-50R and use a plug on the EVSE or want to future proof the pull.
The ground fault breaker is overkill, the EVSE has its own ground fault capabilities. If it is wall mounted and always plugged in, its fine. If you want to argue this point, how many RV receptacles have GFI or even require it? I live in Indiana, so your code requirements may vary. I installed a 100A circuit for an 80A EVSE last August and it is working great. 19kW home charging is amazing!
Generally if you want to pull 50A continuous, your breaker should be sized to 125% of that. 60A, 120% is close enough. If you keep space above this breaker, it will be completely fine. The derating is for a filled load center as the breakers are rated for use in open air for some dumb reason or another.