You can get a slight life extension if you take the nozzle off, put a screw in it, then use a clean spare nozzle, put some cling film [US saran wrap??] over the open end & screw the new nozzle over it.
The screw will pull the hardened silicone out of the used nozzle next time you need it, so you don't overall get through as many nozzles. The cling film will slightly extend the life of the remainder in the tube. I've got a year or two out of opened tubes this way. Acrylic will last even longer; I have 2 tubes of acrylic in colours I can no longer get [without too much effort], used for very specific patch-ups in my bathroom - now 20 years old & still good.