This hole in my basement has a roughed-in drain pipe for a bathtub (can't really see it, but I've verified it's there):
As you can see, it's about 12"x16". As I prepare to finish the basement, I'm not really sure how I ought to handle this hole. Should I just run the subfloor up to the edges of the hole and then leave it as-is? or should I do something to seal it once the plumbing is finished to keep critters/moisture/cold from coming out of it?