How do I wire a thermostat, Simple Comfort2000, red blue white green wires
It's difficult to tell what is being asked here. This question is ambiguous, vague, incomplete, overly broad, or rhetorical and cannot be reasonably answered in its current form. For help clarifying this question so that it can be reopened, see the FAQ.
Is there an existing thermostat? There's not much standardization of the colors used, so you need to explicitly check them: if no existing working thermostat, check what they're connected to inside the furnace on the control board.
Once you figure it out, it's a very good idea to label the wires at your thermostat to avoid any future confusion.
The most common terminals/colors:
This page actually describes the wiring in a lot more detail than I can here: http://wiki.xtronics.com/index.php/Thermostat_signals_and_wiring