I started thinking about this yesterday because I currently have a weird feeling second skin from the polyurethane adhesive I used to attach my kitchen backsplash on Sunday. I foolishly assumed since the instructions say "cleans up with mineral spirits" that cleaning some incidental mess off my fingers wouldn't be a big deal. Boy was I wrong!
Are there any substances you have worked with (adhesives, solvents, caulk, etc etc) that you really wish you had worn gloves (or otherwise not touched with bare skin) when you started working with them?
I'll start with my example:
Avoid getting PL Premium Polyurethane construction adhesive on your bare hands - it is harder to get off bare skin than silicone caulk!